Science Excellence Award 2008

NIS LABS

Contract Research Laboratory

Natural Products Research Strategies


Cell-based/in vitro:  Testing of mechanisms of action in panels of cellular and/or enzymatic assays
   

Antioxidant
Capacity

Anti-
Inflammatory

Immuno-
modulatory

Vascular

Pain
Syndromes

CAP-e (Cell-based Antioxidant Protection
using Erythroctyes

X

CAP-m (Cell-based Antioxidant Protection
of Mitochondria)

X

CAP-a (Cell-based Antioxidant Protection
against Apoptosis)

X

ROS PMN

X

X

Monocyte phagocytosis

X

PMN migration (immune surveillance/ antibacterial/
anti-inflammatory effects)

X

X

PMN migration (immune surveillance/anti-allergic effects)

X

X

Lymphocyte Proliferation Assay 1:  Basic Testing

 

X

Lymphocyte Proliferation Assay 2:  Advanced

 

X

T/B Lymphocyte Activation: Phenotyping

 

X

Cytokine Production

 

X

Natural Killer Cell Activation: Basic Testing

X

Natural Killer Cell Activation:  Advanced

X

Inhibition of COX-2 gene expression

X

Inhibition of COX-2,
Lipoxygenase enzymatic function

X

Clinical/in vivo:  Testing of immediate and/or long-term effects upon consumption

CAP-e in vivo

X

TBARS

X

X

X

hs-C Reactive Protein

X

X

X

Cytokine Production in vivo

 

X

X

X

Skin Testing for Anti-inflammatory Effect

X

Lymphocyte Trafficking

X

Laser Doppler Evaluation, BP ABI

X

Range of Motion, Strength Testing, Pain Threshold Testing

X

Fibrinolytic Capacity

X

 
Sample Submission Forms

CAP-e

General

DOC

 

DOC

PDF

 

PDF

XPS

 

XPS

 


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Last Modified:12/10/08